March 23, 2012
Bontril is one of the brand names for phendimetrazine, a prescription diet aid. It acts as a sympathomimetic amine appetite suppressant, similar to drugs like phentermine. By limiting the number of calories that Bontril users consume, this medication helps to promote weight loss when combined with a healthy diet and exercise plan.
How Bontril Works?
Phendimetrazine is a “prodrug.” This means that it, itself, is broken down into a more active drug- in this case; up to thirty percent of phendimetrazine is metabolized into phenmetrazine. Phenmetrazine triggers the release of norepinephrine and dopamine. Norepinephrine is one of the neurotransmitters involved in triggering the body’s “flight or fight” response to stress. During this response, the body’s appetite is suppressed. By inducing norepinephrine release, phenmetrazine helps dieters lose weight by stifling their urge to eat, and temporarily boosting their metabolisms.
Phendimetrazine uses the same chemical structure as methamphetamines. A methyl group is added to this structure, which makes the stimulating component of phendimetrazine virtually useless. Once this methyl group is metabolized, it causes a slow, steady release of stimulants into the body. Because of its chemical structure, Bontril may trigger a positive result on certain drug tests.
Bontril Side Effects
Bontril is similar to amphetamines, but has a much lower instance of side effects. Nonetheless, the following symptoms have been reported:
- Pulmonary hypertension.
- Valve disease.
- Decreased impulse control.
- Withdrawal symptoms.
- Rapid or irregular heartbeats.
- Restlessness, jittery feelings, or insomnia.
Phendimetrazine is generally only used in the short term. It is used to promote weight loss in people with obesity who have obesity-related health problems (like diabetes, or controlled high blood pressure) and have not responded well to diet and exercise alone.
Bontril is available by prescription only. Since it has a relatively high potential for abuse, it is categorized as a Schedule III controlled substance, which puts it in the same category as drugs like Vicodin, ketamine, and Tylenol 3. According to the Controlled Substances Act, a Schedule III controlled substance cannot be dispensed by anyone other than a doctor or pharmacist. In addition, prescriptions for this drug may not be filled more than six months after the date of issue, and cannot be refilled more than five times for a single prescription. Since there are other weight loss drugs on the market with a lower potential for abuse, Bontril is not prescribed as often as it used to be.
If you have a high BMI, one or more obesity-related illnesses, and have been unable to lose weight successfully in the past, you may be a candidate for Bontril. Your doctor will conduct an exam to determine if Bontril’s potential benefits to you outweigh the risk of unwanted side effects, and prescribe it accordingly. Because Bontril has a relatively high potential for abuse and a risk of serious side effects, it’s important to take it exactly as directed.
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